Healing of a skin wound when using Trigonella foenum‑graecum against the background of experimental steroid hyperglycemia

نویسندگان

چکیده

Purpose. To evaluate the intensity of healing an infected skin wound in rats using Trigonella foenum- graecum (Fenugreek) against background experimental steroid hyperglycemia. Materials and methods. The included study ( n = 20) were divided into two equal groups. First, a model hyperglycemia was created for all animals. Then same animals used to create models wound. first group (the main one) treated with surface ointment containing . Also, extract constantly added water group. Intact vaseline applied second (control) rats. After 5 days, we evaluated regeneration activity, blood glucose levels, panel Results. This showed several positive aspects use foenum-g raecum terms treatment wounds decrease levels almost baseline values oral administration recorded. By end observation, level glycemia times less compared p < 0.05). In group, number leukocytes higher but this difference not significant. However, recorded significant increase granulocytes by more than 0.05), which indicates immunomodulatory property , affected activity way Conclusion. As result study, promising prospects have been obtained plant‑ derived drug correction wounds. Application fenugreek topically form reduced inflammation improved suffering from

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ژورنال

عنوان ژورنال: Issledovaniâ i praktika v medicine

سال: 2023

ISSN: ['2409-2231', '2410-1893']

DOI: https://doi.org/10.17709/2410-1893-2023-10-2-7